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Denise L. Mayfield

Denise L. Mayfield


WSG Practice Industries


Texas, U.S.A.


Denise Mayfield is a certified licensing professional, and routinely drafts, negotiates, and strategizes between multiple parties to provide her client’s with the most advantageous licensing and combination business-focused agreements designed to achieve their business needs. Her experience includes licensing strategies involving intellectual property assets (patents, trademarks, copyright, trade secret), real estate, ongoing business operations (hospitality (restaurant, bar) services), medical devices, beer, whisky, and other branded and unbranded products and future products in development. Denise provides specialized expertise in patent matters related to plant genetics, plant biochemistry, chemical synthesis, aquaculture, organic synthesis chemistry, medical devices, genotyping, and DNA sequencing subject matter areas. Specific types of related, ancillary agreements she has drafted include license-back agreements, product and/or service outsourcing agreements, distribution agreements, joint-development agreements and technology transfer agreements (University, Private entity, Start-up business).

Denise brings sophisticated scientific, commercial and legal experience combining patent, health care, pharma, biotech and software/AI advances to protect client assets.

Denise’s strong science background (with an advanced degree in genetics and physiology, and years of experience as a medical researcher) together with her legal training, brings strategic and technically focused legal services to her clients. A skilled and experienced patent attorney, she assists domestic and international clients in identifying, protecting, licensing and litigating bet-the-company technologies.

Denise works closely with internal corporate and university technology transfer professionals in patent portfolio development and prosecution, product commercialization strategies, technology transfer and regulatory compliance resolution. She represents companies directly in negotiating technology licenses, cooperative research agreements, joint venture agreements, international distribution and marketing programs, patent litigation matters and university pooling arrangements. Her gift for understanding the business needs of the client permits her to create the strongest protection strategy for her clients.

Denise partners with clients to protect a wide range of products and methods, including genetic testing, disease detection and screening tools, veterinary medicine, vaccines, orthopedic devices, dental devices, chemical purification and extraction techniques, plant products, and cannabis and hemp products and their preparation, as well as extraction/purification methods.

Denise counsels clients on matters such as pharmacophore drug modeling and selection, antibody and stem cell technologies, regenerative medicine and stem cell technology, disease-screening methods and bio-signature development and disease detection. She also handles IP matters related to medical devices (spine, shoulder, knee), DEA-regulated research, controlled substances (anabolic steroids, cannabinoids) and Bayh-Dole compliance and iEdison reporting.

Denise negotiates global and regional licenses that drive revenues while allowing clients to retain ownership of intellectual property assets. She has worked in all aspects of the technology transfer process assisting and drafting license agreements, option agreements, and other transactional documents concerning pharmaceuticals (human and veterinary), medical devices, biologics, and health care monitoring wearable technologies. In developing comprehensive licensing strategies for emerging and larger technology companies, Denise takes into account the unique business pressures each group faces. She also has significant experience helping clients divest assets they no longer wish to pursue. 

Denise is a registered patent attorney, admitted to practice before the U.S. Patent and Trademark Office. She works closely with clients to maximize an effective path to market, especially for products, methods and systems related to technologies requiring the experienced handling of FDA regulatory compliance issues and trade secret and/or patented technologies. Denise is admitted to practice in Washington, D.C., Texas, and Colorado, and frequently assists clients in navigating and resolving governmental agency-related and state-compliant issues.

Bar Admissions



District of Columbia

U.S. Patent and Trademark Office


St. Mary's University School of Law, J.D. University of Texas at San Antonio, M.S.
  • Genetics and Physiology
Trinity University, B.A.
  • Biology
Areas of Practice

Biotechnology and Life Science | Cannabis Law | FDA Regulatory | Health Care | Intellectual Property | Intellectual Property Litigation | Non-Compete, Unfair Competition and Trade Secrets | Patent Prosecution | Technology & Sourcing Transactions | Trademark

WSG's members are independent firms and are not affiliated in the joint practice of professional services. Each member exercises its own individual judgments on all client matters.

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